Carotenemia

From iWiki

Carotenemia is a benign condition characterised by the yellow-orange discoloration of the skin and occasionally the eyes due to elevated levels of carotenoids in the blood. Carotenoids are pigments found in certain fruits and vegetables, and their accumulation in the body can lead to changes in skin coloration. While carotenemia is harmless, it is essential to distinguish it from other conditions causing yellow discoloration, such as jaundice.

Causes

The primary cause of carotenemia is an excessive intake of carotenoid-rich foods, particularly those containing beta-carotene. Common sources include:

Carrots

Sweet potatoes

Pumpkins

Mangoes

Spinach

Kale

Squash

Melons

Carotenemia can also result from the consumption of carotenoid-containing supplements or infant foods high in pureed carrots.

Mechanism

Carotenoids are fat-soluble compounds that contribute to the colour of various fruits and vegetables. When consumed, the body converts beta-carotene into vitamin A, an essential nutrient. However, excess carotenoids that are not converted into vitamin A can accumulate in the fat layer beneath the skin, leading to the characteristic yellow-orange discoloration.

Symptoms

The primary symptom of carotenemia is the yellow-orange tint of the skin, which is particularly noticeable on areas with a higher fat content, such as the palms, soles, and the nasolabial folds. The discoloration is typically gradual and painless. Importantly, the whites of the eyes (sclera) remain white, distinguishing carotenemia from jaundice.

Diagnosis

Diagnosing carotenemia involves a thorough medical history and physical examination. Blood tests may be conducted to confirm elevated levels of carotenoids. It is crucial to differentiate carotenemia from jaundice, as the latter may indicate underlying liver or gallbladder issues.

Treatment

Carotenemia is a benign condition, and treatment primarily involves modifying dietary habits. Gradual reduction or elimination of carotenoid-rich foods usually results in the resolution of skin discoloration over time. However, it is important to consult a healthcare professional before making significant dietary changes.

Prevention

Preventing carotenemia involves maintaining a balanced diet and being mindful of carotenoid intake. While these pigments are essential for health, moderation is key to avoiding their excess accumulation in the body.

Conclusion

Carotenemia is a harmless condition resulting from the accumulation of carotenoids in the body, primarily due to excessive dietary intake. Distinguishing it from jaundice is crucial for an accurate diagnosis. With dietary modifications, carotenemia typically resolves without any long-term consequences.